By Prof. Raphael Nyarkotey Obu
Electrolytic Ozonated Water
Recently, I chanced on bottled water in Ghana with the inscription “ozonated water”. As a Professor of Naturopathy and a researcher, I decided to investigate why this bottled water is infused with ozone. Whatis ozonated water?
Ozonated water iswater that has been treated with ozone gas.In this article, I examine the evidence on ozonated water, including how it is made, its uses, benefits, andpotential weaknesses. The purpose of my scientific articles on natural remedies is to educate the public and not to provide medical advice.
Ozonated Water?
Ozone is a colorless and odorless gas made up ofthree oxygen atoms. An article by Jillian Kubala, (2020) explains that in the gaseous form, ozone is an unstable molecule that can cause damage to the lungs when inhaled(as cited in Azuma et al., 2014).
A previous study by Elvis and Ekta, (2011) also found that when one dissolves ozone in water, the water becomes ozonated and could have some therapeutic effects, including antioxidant and antimicrobial properties. It can therefore be usedfordental services, cancer treatment, and food safety techniques.
The Making of Ozonated Water
Using an Ozone Generator to make ozonated water
For one to makeozonated water, one needs tofill a cylinder with purified water and allow theozone gas mixture to lather inside. The process can take about 5 minutes until the maximum saturationlevel is reached.
Ozone as a stand-alone gas is likely to cause havocto the respiratory system. Hence, Ozonated water isthe best to use than the ozone gas itself. Studies have demonstrated the therapeutic effects of ozonated water (Kuroda et al., 2015; Smith et al., 2017; Remondino and Valdenassi, 2018).
An article by Carrie Madormo and Erika Klein(2020) asserted that ozone in the olden days was prescribed to treat many sicknesses. The challenge was that they were based on introspections and not on science. This notwithstanding, according to Gerard V. Sunnen, (2005), a Medical Doctor agrees thatsome introspections were validatedscientifically.
Ozonated water; the Science
Cancer treatment and prevention
Due to the limitations and side effectsof conventional cancer treatment, Höckel and Vaupel(2001) study found that ozonated water may improve the efficacy of chemotherapy drugs in targeting tumors. The same authors further warned that these findings were based on a rat study and that human trials had not been conducted.
A prospectivestudy by Chevrier et al., (2004) also examinedthe risk of gettingbladder cancer in adults who drank ozonated water compared with chlorinated water. The study found that the risk of developing bladder cancer was lower in the cohort whoconsumed ozonated water.
Dental remedy
In dentistry, Ozone is sometimes used as a treatmentmodality. Saini, (2011) and Tiwari et al.,(2017) studies found that in dentistry, ozone is used to clear bad bacteria from the mouth and support the healing of oral wounds.
Anumulaet al., (2017) study tested the efficacy of ozonated water on tooth decay as an alternative to a chlorhexidine mouth rinse. The study involved 23 adults who had salivary samples taken at 7 and 14 days of continued use of ozonated water. The study found that there was a momentous decrease in Mutans Streptococci, a bacterium found on teeth that increases the risk of tooth decay. This study was in agreement with Tiwari et al., (2017) who also found that administering ozonated water to an oral wound sped the healing process by increasing cell turnover.
Antioxidant and antimicrobial
Smith et al., (2017) study found that contact with ozone gas may trigger a stress response in the body. The study further notes that this response may activate the production of many antioxidants that help clear free radicals from the body.
Bonforte et al., (2013) further reported a case study of a 62-year-old woman which proved the effects of using ozonated water, in addition to antibiotics, to treat an infection (UTI). In this study, ozonated water was administered into the urinary tract 3 times over 1 week. The case study further found that the patient recovered from the UTI, and no reinfection reoccurredin the 4-month follow-up.We couldhowever argue that this study examined one personusingantibiotics andozonated water at the same,hence, we cannot say whether the patient’s recovery was due to the ozonated water or the antibiotics. Nevertheless, Bonforteet al., (2013) found that ozonated water may speed the cell repair process, reducing bacteria and indications linked to urinary tract infections.
Apart from the antioxidant properties, Marco and Luigi, (2018) note that ozonated water may increase microbes’ sensitivity to antibiotic treatment.
Food safety and water purification
Due to itsantibacterial properties and ability to destroy industrial impurities, ozone is regarded as an importantalternative to chlorine(Sunnen, 2005; Marco and Luigi, 2018).
Sunnen, (2005) further explains that one city in Germany and France became the first in 1901 to use ozone to purify drinking water. Sunnen, (2005) also positsthat, in the modern dispensation, there are over 3,000 citiesemploying ozone to purify their drinking water. A recent study by Sarron et al., (2021) reports that the United States Food and Drug Administration (FDA) listed ozone as “generally recognized as safe” when used in bottled wateras well as food.
Ozonated water is also effective and safe to wash fresh vegetables to decrease the bacteria loads on the surface and support preservation(Beltran et al., 2005; Sarron et al., 2021). It should however be used in a controlled environment.
Warnings
A study by Zhang etal., (2019) found that ozone gas is regardedas a pollutant, and produces an inflammatory response that is likely to trigger airwaydamage if ingested. Zhang et al., (2019) also explained that short-term exposure is known to worsen respiratory symptoms in adults and children.
Two studies(Kavlock et al, 1980; Salam et al., 2005) found that ozone might contribute to low birth weight if exposure takes place during the second or third trimester. An extensive review of the literature has revealed that most studies examine the effects of ozone gas rather than the effects of ozonated water. Additionally, there does not appear to be any research linking respiratory symptoms or low birth weights to ozonated water( Fatima Hallal, 2021).
Ozone gas has to be handled or administered especially in Naturopathic practice by a qualified practitioner as an unqualified practitioner is likely to expose you to risks. The interesting thing is that therisks complained of are not fully understood.
SUMMARY
In summary, Fatima Hallal, (2021)asserts that ozonated water has antibacterial and antioxidant-promoting properties. Additionally, according to the scientific literature, if Ozone is managed safely, is likely to avert tooth decay, lessen bladder cancer risk, purify drinking water, and improve the effectiveness of cancer treatment.
Take-Home
Fatima Hallal, ( 2021) provides a summation of zone water:
- While ozone gas may pose some health risks, ozonated water continues to demonstrate therapeutic potential.
- The FDA considers ozonated water to be safe when it comes to drinking and coming into contact with food.
- In a controlled environment, such as in industrial water plants or under medical supervision, there is evidence that ozonated water may be safe to drink and use in some medical therapies.
- However, more research is needed to support the safety and benefits of ozonated water for oral consumption.
The writer is a Professor of Naturopathic Healthcare, President of the Nyarkotey College of Holistic Medicine & Technology (NUCHMT), and the African Naturopathic Foundation.E-mail: [email protected].
References
Azuma K, Mori T, Kawamoto K, Kuroda K, Tsuka T, Imagawa T, Osaki T, Itoh F, Minami S, Okamoto Y. Anti-inflammatory effects of ozonated water in an experimental mouse model. Biomed Rep. 2014 Sep;2(5):671-674. doi: 10.3892/br.2014.290. Epub 2014 May 26. PMID: 25054009; PMCID: PMC4106612.
Elvis AM, Ekta JS. Ozone therapy: A clinical review. J Nat Sci Biol Med. 2011 Jan;2(1):66-70. doi: 10.4103/0976-9668.82319. PMID: 22470237; PMCID: PMC3312702.
Bocci V. (2010). Preparation of Ozonated Water and Oil for the Topical Therapy – Ozone as a Drinking Water Disinfectant: Ozone Disinfection to Prevent Nosocomial Infections. OZONE: A new medical drug, 9–16. https://doi.org/10.1007/978-90-481-9234-2_3
Kuroda K, Azuma K, Mori T, Kawamoto K, Murahata Y, Tsuka T, Osaki T, Ito N, Imagawa T, Itoh F, Okamoto Y. The Safety and Anti-Tumor Effects of Ozonated Water in Vivo. Int J Mol Sci. 2015 Oct 22;16(10):25108-20. doi: 10.3390/ijms161025108. PMID: 26506343; PMCID: PMC4632793.
Smith, N. L., Wilson, A. L., Gandhi, J., Vatsia, S., & Khan, S. A. (2017). Ozone therapy: an overview of pharmacodynamics, current research, and clinical utility. Medical gas research, 7(3), 212–219. https://doi.org/10.4103/2045-9912.215752
Gerard V. Sunnen(2015) Ozone in Medicine: Overview and Future Directions. Ozonics Internationals
Höckel M, Vaupel P. Tumor hypoxia: definitions and current clinical, biologic, and molecular aspects. J Natl Cancer Inst. 2001 Feb 21;93(4):266-76. doi: 10.1093/jnci/93.4.266. PMID: 11181773.
Chevrier C, Junod B, Cordier S. Does ozonation of drinking water reduce the risk of bladder cancer? Epidemiology. 2004 Sep;15(5):605-14. doi: 10.1097/01.ede.0000134866.61780.28. PMID: 15308961.
Saini R. (2011). Ozone therapy in dentistry: A strategic review. Journal of natural science, biology, and medicine, 2(2), 151–153. https://doi.org/10.4103/0976-9668.92318
Anumula L, Kumar KS, Krishna CM, Lakshmi KS. Antibacterial Activity of Freshly Prepared Ozonated Water and Chlorhexidine on Mutans Streptococcus When Used as an Oral Rinse – A Randomised Clinical Study. J Clin Diagn Res. 2017 Jul;11(7):ZC05-ZC08. doi: 10.7860/JCDR/2017/26708.10129. Epub 2017 Jul 1. PMID: 28893032; PMCID: PMC5583811.
Bonforte G, Bellasi A, Riva H, Ferradini M, Arrighi E, Groppi G, Minoretti C, Franzini M. Ozone Therapy: Un potenziale approccio alla infezioni delle basse vie urinarie? A Case Series Report [Ozone therapy: a potential adjunct approach to lower urinary tract infection? A case series report]. G Ital Nefrol. 2013 Jul-Aug;30(4):gin/30.4.16. Italian. PMID: 24403204.
Sarron, E., Gadonna-Widehem, P., & Aussenac, T. (2021). Ozone Treatments for Preserving Fresh Vegetable Quality: A Critical Review. Foods (Basel, Switzerland), 10(3), 605. https://doi.org/10.3390/foods10030605
Zhang, J. J., Wei, Y., & Fang, Z. (2019). Ozone Pollution: A Major Health Hazard Worldwide. Frontiers in immunology, 10, 2518. https://doi.org/10.3389/fimmu.2019.02518