What you and your partner should know about your blood type before tying the knot


Do you have a son/daughter who wishes to spend the rest of their lives with that handsome guy or that amazing girl but has little or no knowledge whatsoever about their blood genotypecompatibility?

More often than not, the youth of the 21st Century jump into marriages with less or no information about their individual blood genotypes and their blood groups. This however, sometimes leads to severe health problems for the children they bear later in the marriage.

It is important to know that each blood genotype has its appropriate suitor.

When it comes to blood groups of couples, they are generally compatible with each other. This means that any 2 people can get married irrespective of their blood groups. The problem however has to do with the RHESUS FACTOR (i.e the positive {+} and negative {-} ) associated with each blood group. If a couple are both rhesus positive {+} or both rhesus negative {-} or the man alone is rhesus negative {-}, then there’s no cause for alarm. In the case where the man is rhesus positive {+}, the wife is rhesus {-} and their first child is rhesus positive {+}, then subsequent children who are rhesus positive {+} are at risk of Hemolytic Disease of the Newborn (HDN) which may lead to anaemia and/or jaundice in the child. The good news is that the pregnant rhesus negative {-} mother with a rhesus positive {+} spouse can get an immunoglobulin shot(RhoGam) which will protect her unborn child.

Blood Genotypes

AA+ AA = Excellent

AA+ AS = Good

AA+ SS = Good

AA + SC = Good

AA + AC = Good

AA + CC = Good

AC + AC = Good

AS + AS = Bad

AS + AC = Bad

AS + SC = Very Bad

AC + SC = Very Bad

AS + SS = Very Bad

SC + SC = Extremely Bad

SC + SS = Extremely Bad

SS + SS = Extremely Bad


Blood groups

It is relevant to know your blood type and how common it is; the possible blood groups of your children; and the blood types you are compatible with for transfusion.

(O+)…..37.4% (most common)







(AB-)…..0.6% (rarest)


Blood group Combinations with possible groups of children

If both parents are rhesus negative, then all children will be rhesus negative.

If both parents are rhesus positive, then all children will be rhesus positive.

If one parent is rhesus negative and the other is rhesus positive, the children can either be rhesus positive or negative.

O & O = O

O & A = O, A

O & B = O, B

O & AB = A, B

A & A = O, A

A & B = O, A, B, AB

A & AB = A, B, AB

B & B = O, B

B & AB = A, B, AB

AB & AB = A, B, AB


Compatible blood groupsfor blood donation

O- can only receive O-

O+ can receive O+, O-

  • can receive A-,O-

A+ can receive A+, A-, O+, O-

  • can receive B-, O-

B+ can receive B+, B-,O+,O-

AB- can receive AB-, B-,A-, O-

AB+ can receive AB+,AB-,B+,B-,A+,A-,O+, O-

When you know your blood genotype, it helps you to make the right choices that will not harm the future of your children with diseases such as sickle cell anaemia. Knowing your blood group as well as your spouse’s gives you an idea of the possible blood groups of your children. Knowledge of your blood group also makes it easier for you to make decisions when it comes to blood donations.


Afia Serwaa Opare


Source: Dr. Alex Vico-Korda

Ridge hospital





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